Absolutely. The difference between the variants comes down to how the gain is apportioned between stages and the tone shaping in various places. As much as I like the Screw Driver, the MOSFET front-end is too noisy. I prefer a JFET there, although a BJT works well too. Getting the bias right with the Screw Driver and Hybrid Fuzz Driver is tricky due to the germanium transistor, but it's doable and sounds great when dialed-in.