Do you mean for actual high gain pedals or for pedals when you're running your chain high gain?
If it's specifically for higher gain effects I realistically see three options to avoid using one;
1) Higher supply voltage.
2) Rail-to-Rail op-amps.
3) Bootstrapping op-amp outputs.
For things with clocks you can sometimes be a little cheeky and use the inbuilt oscillator to do some charge pumping for you for a little extra juice...