Orientation and wiring looks good. Where did you get your 2n5457 from? These are discontinued so you may have a fake.
As Barry mentioned, you've got a few cold joints. Go ahead and reflow any solder that looks dull and gray, or where they don't seem to be 'sticking' to the leads. Your solder should be nice and shiny. Just touch the iron to them for a few seconds, some flux will help too if you have it.
Some of your component leads still look a bit long and could be shorting. Trim them down and clean the board with isopropyl alcohol.
If you're still having issues, you'll have to go through and verify all your resistors and capacitors are the correct values.
If that doesn't do it, time to get out the audio probe and track down the issue!