You can get micro amounts of lead from handling your solder, and like comradehoser said, you can get from touching the solder side of the board. It is a precautionary step in clean-up so it doesn't absorb through skin or be injested when you eat after working on a pcb. Lead is one of those elements that builds up in your body without any immediate effects, however you can prevent that by washing your hands each time you get up from your workstation. The rosin fumes are the real problem, you don't definitely don't need to breathe those in. I can circumvent the handwashing by wearing some nitrile gloves.