best use of your time troubleshooting is to get the schematic for your build and use your digital multimeter to make sure that the parts connect together the way they are laid out in the schematic. if everything connects the way it should, then you check to make sure there are no "extra" connections to ground in the parts that carry the audio signal and the power. when you find parts that should connect but do not, you figure out what the problem is and fix it (usually a bad connection to the board, which is why the first advice given is usually to check the connections on the board and touch up anything that looks questionable).